Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone

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Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone.

Hydroquinone (HQ) has been reported to produce chromosomal effects in some in vivo and in vitro animal models. Its potential for inducing similar effects in human lymphocytes is less clear. The purpose of this study was to examine human lymphocytes treated with HQ for the presence of chromosomal anomalies, using an accepted assay for micronuclei. In addition, the stability of HQ in culture medi...

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Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes.

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ژورنال

عنوان ژورنال: Mutagenesis

سال: 2000

ISSN: 1464-3804

DOI: 10.1093/mutage/15.6.479